Molybdenum-100 Targets for Cyclotron Production of Technetium-99m

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  • A process for manufacturing targets for technetium-99m production, via 100Mo(p, 2n)99mTc, is presented. Targets consist of a thin layer of molybdenum-100 pressed into a copper heat sink complete with water cooling channels and O-rings. These targets are designed to be irradiated in cyclotrons at hospitals and regional pharmacies around the world to replace fission produced 99Mo.The iterations and tests leading to the final target design and processing procedures are presented. Physical descriptions of the targets are given, followed by the procedure for manufacture, and process improvements for large-scale production.The importance of 99mTc as a diagnostic imaging tool is presented, with references to instability of current sources and recent shortages, which have had led to world-wide efforts to develop non-reactor produced isotopes.

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  • Copyright © 2015 the author(s). Theses may be used for non-commercial research, educational, or related academic purposes only. Such uses include personal study, research, scholarship, and teaching. Theses may only be shared by linking to Carleton University Institutional Repository and no part may be used without proper attribution to the author. No part may be used for commercial purposes directly or indirectly via a for-profit platform; no adaptation or derivative works are permitted without consent from the copyright owner.
Date Created
  • 2015


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