Determination of Radionuclides in Biological Samples by Liquid and Solid Phase Extraction

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  • Radionuclide separation and preconcentration methods were developed for two types of biological samples that play a role in assessing internal radiation contamination. For the determination of Pu-238 in urine, either as a single isotope or in a mixture, a dispersive liquid-liquid microextraction technique was used for extraction. Parameters including dispersers, extractants, back extractants and pH were optimized to achieve high recoveries of plutonium. Liquid scintillation counting was used for samples containing only plutonium, and alpha spectroscopy was used for samples containing a mixture of isotopes. For the determination of Am-241 in a humerus from a deceased worker exposed to americium 40 years prior, subsamples were taken by shaving successive layers off the bone (from the periosteum to the marrow) for dry/wet ashing before americium was isolated by extraction chromatography and determined using alpha spectrometry. The results showed americium retention and migration throughout the total bone volume.

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  • Copyright © 2016 the author(s). Theses may be used for non-commercial research, educational, or related academic purposes only. Such uses include personal study, research, scholarship, and teaching. Theses may only be shared by linking to Carleton University Institutional Repository and no part may be used without proper attribution to the author. No part may be used for commercial purposes directly or indirectly via a for-profit platform; no adaptation or derivative works are permitted without consent from the copyright owner.
Date Created
  • 2016


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