Investigating a Role for BLADE-ON-PETIOLE Genes in Plant Defense

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  • Plants have evolved multiple layers of defense to ward off pathogens. Pathogen-associated molecular pattern (PAMPs)-triggered immunity (PTI) is the most ancient and basal form of plant defense. BLADE-ON-PETIOLE1/2 (BOP1/2) are members of an evolutionarily conserved subclade of BTB-ankyrin proteins that control plant development within the NON-EXPRESSOR OF PATHOGENESIS-RELATED GENES1 (NPR1) family of plant defense regulators that control systemic acquired resistance. I analyzed the transcriptome of BOP1 overexpressing plants to find a previously undiscovered role for BOPs in plant defense. Gene Ontology analysis revealed that 35% of upregulated genes belong to plant defense pathways with PTI forming the largest group. Among these PTI genes were clade I TGA factors, also essential for BOP-mediated developmental processes. Data validation and direct pathogen testing support the model that BOPs and clade I TGAs co-regulate a subset of genes involved in PTI. These data uncover dual role for Arabidopsis BOPs in development and defense.

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  • Copyright © 2018 the author(s). Theses may be used for non-commercial research, educational, or related academic purposes only. Such uses include personal study, research, scholarship, and teaching. Theses may only be shared by linking to Carleton University Institutional Repository and no part may be used without proper attribution to the author. No part may be used for commercial purposes directly or indirectly via a for-profit platform; no adaptation or derivative works are permitted without consent from the copyright owner.
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  • 2018


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